About our research
Research institutes
This Master's specialisation is closely connected to the Radboud Institute for Molecular Life Sciences (RIMLS), a leading interfaculty research institute of the Faculty of Science and the uu77 Medical Centre (Radboudumc). By integrating the scientific expertise of both the molecular and medical sciences, RIMLS aims to achieve a better understanding of the molecular mechanisms of diseases. RIMLS's research areas include epigenetics, stem cell and developmental biology, and bioinformatics.
Research departments
During your Master's internship, you’ll spend more than half of your time in a laboratory. In that way, you’ll get extensive hands-on research experience. You can choose to do your internship at a research department at RIMLS, or elsewhere. Some relevant departments are:
The department Human Biology aims to understand fundamental questions regarding the regulation of gene expression by chromatin architecture, the impact of cellular metabolism and the (micro)environment on the formation of chromatin states and transcriptional variability. The department is particularly interested in understanding these pathways during ageing and age-related diseases.
The department of Human Genetics treats and investigates hereditary diseases of patients and their families. Their research is focused on the characterisation of novel diseasegenes and also results in new therapeutic strategies. Topics of interest are: blindness and deafness, cancer, congenital anomalies, and mental handicaps.
This department aims to unravel the molecular basis of development and differentiation emanating from the genome and epigenome in the context of health and disease. The major focus is on the regulatory networks in several model systems. State-of-the-art technological developments are applied, ranging from single molecule studies to genome wide elucidation of genetic and epigenetic pathways and mechanisms.
The Nephrology department is a full facility center for renal replacement therapy and provides all dialysis modalities. Furthermore, renal transplantations are performed with kidneys from both living and cadaveric donors. The clinical and fundamental research of this department is focused on glomerular diseases and renal transplantation.
The department Haematology performs research into blood-related diseases. The department is highly involved in supportive care studies for malignant diseases, which for example aim to optimize the tolerability of intensive chemotherapy. Other focus areas are immunotherapy, bone marrow diseases and meyelodysplastic syndrome.
Research of this department focuses on personalized pharmacotherapy and systems pharmacology/toxicology ranging from molecule to patient. It aims to improve the efficacy and safety of drugs, including drug overdoses and intoxications. They investigate the complete spectrum from the molecular to the clinical level.
Researchers
Get to know our researchers and their work, you could be working alongside them in this Master's!
Research projects
Have a look at what our researchers are currently working on.
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Stochasticity
Research into the molecular regulation of early embryonal development
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Genetic Plasticity
This project aims to improve the chances of successful pregnancy upon IVF by discovering how chromosomal abnormalities affect early embryonal development.
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CorneaRegID
Current treatments for cornea damage depend on stem cells in the patient's own healthy eye. This project will develop a novel regenerative technology to convert patient's skin and mouth cells into cornea stem cells to restore vision.