About our research
Research institute
This Master's specialisation is closely connected to the Radboud Institute for Molecular Life Sciences (RIMLS), a leading research institute where (bio)molecular research is conducted in collaboration with the Radboudumc Research Institute for Medical Innovation. By integrating the scientific expertise of both the molecular and medical sciences, RIMLS aims to achieve a better understanding of the molecular mechanisms of diseases. RIMLS's research areas include epigenetics, stem cell and developmental biology, and bioinformatics.
Radboud Institute for Molecular Life Sciences (RIMLS)
Research departments
During your Master's you will do at least one internship at one of our research departments. Relevant departments are:
The Molecular Biology department focuses on genetic and epigenetic pathways in health and disease. Sometimes they zoom in on one specific protein, but often the research encompasses genome and proteome wide elucidation of complete molecular mechanisms. This includes the analysis of transcription factor binding, 3D structures, epigenetic marks, DNA-methylation, RNA transcriptomes and epigenetic reader complexes. With both next-generation sequencing techniques and state-of-the-art quantitative mass-spectrometry genomics, epigenomics and proteomics are combined in one cellular approach.
A central theme in the research of the department of Molecular Developmental Biology is developmental gene regulation. They work on questions like: Which genes play a role in cell development? What is the role of epigenetic mutations in their transcription? And how can we use bioinformatics to study interactions between DNA and proteins? The answers lead to an extended knowledge on pluripotency, cell lineage commitment and various diseases.
This department investigates the regulatory systems at the single-cell level to address fundamental questions and diseases, including aging, immunity, and cancer.
Researchers
Get to know our researchers and their work, you could be working alongside them in this Master's!
Research projects
Discover what our researchers are currently working on.
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Host4Hypnozoites
Hypnozoites are dormant malaria parasites in the liver that can reactivate without a mosquito bite. This project aims to understand their dormant state and reactivation, and to develop new imaging and therapeutic strategies.
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Genetic Plasticity
This project aims to improve the chances of successful pregnancy upon IVF by discovering how chromosomal abnormalities affect early embryonal development.
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CorneaRegID
Current treatments for cornea damage depend on stem cells in the patient's own healthy eye. This project will develop a novel regenerative technology to convert patient's skin and mouth cells into cornea stem cells to restore vision.